| Motherboard chipset | AMD X399 |
| LAN controller | Intel® X550-AT2, Realtek RTL8211E |
| Supported memory clock speeds | 2133,2400,2666,2933,3200,3600 MHz |
| Parallel processing technology support | Quad-GPU CrossFireX |
| Supported UDIMM module capacity | 4GB, 8GB, 16GB, 32GB |
| Disk on Module (DOM) power connector | Y |
| Maximum internal memory | 256 GB |
| On-board graphics card memory | 16 MB |
| PCI Express x16 (Gen 3.x) slots | 5 |
| PCI Express x4 (Gen 2.x) slots | 1 |
| Number of chassis fan connectors | 6 |
| Supported UDIMM clock speeds | 2133,2400,2666 MHz |
| Compatible operating systems | Windows 10 (x64) Linux RedHat Enterprise Linux Server 7.3 (x64) / 7.6 (x64), CentOs 7.3 (x64) / 7.6 (x64), UBuntu 16.04 (x64) / 18.04 (x64) VMWare ESXi 6.5 u1 |
| Compatible processor series | AMD Ryzen™ Threadripper™, AMD Ryzen™ Threadripper™: The Second Generation |
| Processor socket | Socket TR4 |